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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKCQ
All Species:
35.15
Human Site:
S212
Identified Species:
51.56
UniProt:
Q04759
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04759
NP_006248.1
706
81865
S212
V
I
A
K
C
T
G
S
A
I
N
S
R
E
T
Chimpanzee
Pan troglodytes
XP_001147999
706
81847
S212
V
I
A
K
C
T
G
S
A
I
N
S
R
E
T
Rhesus Macaque
Macaca mulatta
XP_001083320
1140
127261
T675
I
I
G
R
C
T
G
T
A
A
N
S
R
D
T
Dog
Lupus familis
XP_849292
706
81555
S212
V
I
A
K
C
T
G
S
A
I
N
S
R
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q02111
707
81555
S212
V
I
A
K
C
T
G
S
A
I
N
S
R
E
T
Rat
Rattus norvegicus
Q9WTQ0
707
81732
S212
V
I
A
K
C
T
G
S
A
I
N
S
R
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509836
708
81415
S212
V
I
A
K
C
T
G
S
A
V
N
S
R
E
T
Chicken
Gallus gallus
NP_001006133
699
80179
T209
I
I
G
R
C
T
G
T
A
A
N
S
R
D
T
Frog
Xenopus laevis
Q7LZQ8
671
76506
L188
V
P
M
D
P
N
G
L
S
D
P
Y
V
K
L
Zebra Danio
Brachydanio rerio
Q7SY24
670
76288
L197
L
S
D
P
Y
V
K
L
K
L
I
P
D
P
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13678
634
71138
V192
H
K
R
C
Q
K
N
V
A
N
T
C
G
I
N
Honey Bee
Apis mellifera
XP_394743
624
71014
T186
P
H
R
F
R
L
H
T
F
M
S
P
T
F
C
Nematode Worm
Caenorhab. elegans
P34722
704
80280
S218
V
I
M
Q
C
P
G
S
A
K
N
T
K
E
T
Sea Urchin
Strong. purpuratus
XP_787505
585
66691
N186
N
V
H
H
K
C
K
N
N
V
P
N
L
C
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P24583
1151
131500
F440
D
F
L
R
Y
T
G
F
Q
C
Q
D
C
K
F
Red Bread Mold
Neurospora crassa
P87253
1142
127954
I506
T
S
V
V
T
K
C
I
S
K
S
N
A
E
T
Conservation
Percent
Protein Identity:
100
99.7
33.6
96.7
N.A.
94.7
94
N.A.
86.1
63.3
33.9
34.1
N.A.
42.9
43.2
47.1
47.8
Protein Similarity:
100
99.7
45.1
98.3
N.A.
97.5
96.8
N.A.
92.9
77.1
48.2
49.2
N.A.
58.7
58.9
64.1
62
P-Site Identity:
100
100
60
100
N.A.
100
100
N.A.
93.3
60
13.3
0
N.A.
6.6
0
60
0
P-Site Similarity:
100
100
86.6
100
N.A.
100
100
N.A.
100
86.6
26.6
13.3
N.A.
6.6
20
80
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.2
26.5
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
39.3
40.2
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
38
0
0
0
0
0
63
13
0
0
7
0
0
% A
% Cys:
0
0
0
7
57
7
7
0
0
7
0
7
7
7
7
% C
% Asp:
7
0
7
7
0
0
0
0
0
7
0
7
7
13
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
50
0
% E
% Phe:
0
7
0
7
0
0
0
7
7
0
0
0
0
7
7
% F
% Gly:
0
0
13
0
0
0
69
0
0
0
0
0
7
0
7
% G
% His:
7
7
7
7
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
13
57
0
0
0
0
0
7
0
32
7
0
0
7
0
% I
% Lys:
0
7
0
38
7
13
13
0
7
13
0
0
7
13
7
% K
% Leu:
7
0
7
0
0
7
0
13
0
7
0
0
7
0
7
% L
% Met:
0
0
13
0
0
0
0
0
0
7
0
0
0
0
0
% M
% Asn:
7
0
0
0
0
7
7
7
7
7
57
13
0
0
7
% N
% Pro:
7
7
0
7
7
7
0
0
0
0
13
13
0
7
0
% P
% Gln:
0
0
0
7
7
0
0
0
7
0
7
0
0
0
0
% Q
% Arg:
0
0
13
19
7
0
0
0
0
0
0
0
50
0
0
% R
% Ser:
0
13
0
0
0
0
0
44
13
0
13
50
0
0
0
% S
% Thr:
7
0
0
0
7
57
0
19
0
0
7
7
7
0
63
% T
% Val:
50
7
7
7
0
7
0
7
0
13
0
0
7
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
13
0
0
0
0
0
0
7
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _